The overall aim of the initiative is to quantitatively describe the fundamental mechanics and fine-tuned modulation of cytoskeletal dynamics to understand the generation of movement within individual cells (including neurons) and during brain development. To achieve this goal, we bring together a unique set of competencies and skills spanning across physics, chemistry, and biology, developing new methodological and experimental strategies.

Research

CCP Groups

Group leader	Research team	Research focus	Affiliation
Marek Piliarik	Nano optics	Dynamics of single proteins	Institute of Photonics and Electronics, CAS TPC group associated to DIGS-ILS
Zdenek Lansky	Biophysics of cytoskeletal networks	Biophysics of Cytoskeletal networks	Institute of Biotechnology, CAS TPC group associated to DIGS-ILS
Marcus Braun	Neuronal cytoskeleton	Neuronal cytoskeleton	Institute of Biotechnology, CAS
Vladimir Varga	Laboratory of cell motility	Cell motility	Institute of Molecular Genetics, CAS TPC group associated to DIGS-ILS
Martin Balastik	Laboratory of Molecular Neurobiology	Molecular Neurobiology	Institute of Physiology, CAS TPC group associated to DIGS-ILS
Lenka Libusová	Mammalian cytoskeleton	Mammalian cytoskeleton	Faculty of Science, Charles University
Teije Middelkoop	Developmental mechanobiology	Developmental mechanobiology	Institute of Molecular Genetics Czech Academy of Sciences
Michal Cifra	Bioelectrodynamics	Engineering electromagnetic field-biomatter interaction	Institute of Photonics and Electronics, CAS
Milan Vala	Nano Optics	Super-resolution scattering microscopy	Institute of Photonics and Electronics, CAS

DIGS-BB Groups associated to the TPC

Group leader	Research focus	Affiliation	More information
Stefan Diez	Molecular transport in cell biology and nanotechnology	TUD B CUBE, TUD PoL	Stefan Diez Group at DIGS-BB
Elisabeth Fischer-Friedrich	Mechanics of active biomaterials	TUD PoL	Elisabeth Fischer-Friedrich Group at DIGS-BB
Benjamin Friedrich	Biological Algorithms: Spatio-temporal dynamics of cells and tissues	TUD PoL, TUD cfaed	Benjamin Friedrich Group at DIGS-BB
Rolf Jessberger	Chromosome Dynamics and Hematopoietic Cell Biology	TUD MTZ	Rolf Jessberger Group at DIGS-BB
Michele Solimena		TUD PLID	Michele Solimena Group at DIGS-BB
Jared Sterneckert	iPS Cells and Neurodegenerative Diseases	TUD CRTD	Jared Sterneckert at DIGS-BB